Histone 3 anticorps (H3K27me3) (AbBy Fluor® 350)

N° du produit ABIN873719

L’anticorps Lapin Polyclonal anti-Histone 3 a été validé pour WB et FACS. Il convient pour détecter Histone 3 dans des échantillons de Humain et Souris.

Aperçu rapide pour Histone 3 anticorps (H3K27me3) (AbBy Fluor® 350) (ABIN873719)

Antigène: Histone 3 (H3) (Histone H3 (H3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone 3 est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-Histone 3 anticorps (AbBy Fluor® 350)

Épitope: H3K27me3

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic methyl peptide derived from human Histone H3 around methylation site of Lys27

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Histone 3

Antigène: Histone 3 (H3) (Histone H3 (H3))

Autre désignation: Histone H3

Sujet:

Synonyms: Histone H3, H3 histone family member E pseudogene, H3F3, HIST3H3, Histone H3 3 pseudogene.

Background: Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.

ID gène: 3020